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Image Search Results
Journal: BMC Nephrology
Article Title: Expression and significance of Fractalkine/CX3CL1 in MPO-AAV-associated glomerulonephritis rats
doi: 10.1186/s12882-024-03565-3
Figure Lengend Snippet: Schematic illustration of the experimental procedures. Myeloperoxidase(MPO), myeloperoxidase and anti-neutrophil cytoplasmic antibody associated vasculitis (MPO-AAV), anti-fractalkine (anti-FKN)
Article Snippet: Myeloperoxidase (MPO, Sigma-Aldrich, M6908-5UN), Freund’s complete adjuvant (Sigma-F5881), MPO-ANCA-IgG ELISA Kit (CB-E08675R; Cusabio Ltd., Wuhan, China),
Techniques:
Journal: Proceedings of the National Academy of Sciences of the United States of America
Article Title: Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy
doi: 10.1073/pnas.2112561118
Figure Lengend Snippet: Schematic representation of microglial regulation of retinal capillary constriction. Data from this study show microglia are structurally and functionally capable of involvement in the neurovascular unit. Microglia contact neuronal synapses and retinal capillaries (including pericytes) and activation of fractalkine-Cx3cr1 signaling results in capillary constriction, which is via an AT1R-dependent mechanism. Ultimately, capillary regulation may occur via direct microglial mechanism or may involve contributions from pericytes and Müller cells. EC, endothelial cell; PC, pericyte.
Article Snippet:
Techniques: Activation Assay